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Navigating Childhood Seizures Understanding the Expertise of Dr Shlomo Shinnar

  • Dec 30, 2025
  • 4 min read

Childhood seizures can be frightening for families and challenging for healthcare providers. Understanding when to start or stop treatment, predicting outcomes, and managing the broader impact on children and their families requires deep expertise. Dr. Shlomo Shinnar, a neurologist, pediatrician, and epidemiologist, has dedicated his career to advancing knowledge in childhood seizure disorders. His work combines clinical care, long-term studies, and clinical trials to improve outcomes for children with epilepsy and related conditions.


This post explores Dr. Shinnar’s contributions to epilepsy management, his research focus areas, and how his work helps families and clinicians navigate the complexities of childhood seizures.



Dr. Shinnar’s Background and Areas of Expertise


Dr. Shinnar’s unique combination of specialties—neurology, pediatrics, and epidemiology—allows him to approach childhood seizures from multiple angles. His clinical experience in child neurology is paired with a strong research foundation in epilepsy and its long-term prognosis. He also co-directs the Einstein NeuroNEXT Center of Excellence for Clinical Trials in Neurology, which focuses on advancing treatments through rigorous studies.


His expertise covers:


  • Comprehensive epilepsy management in children

  • Prognosis of childhood seizure disorders

  • Clinical trials in neurology, especially epilepsy

  • Research on seizure treatment timing and outcomes

  • Study of epilepsy comorbidities and family impact


This broad skill set enables Dr. Shinnar to address not only the seizures themselves but also the broader challenges faced by children and their families.


Understanding Childhood Seizures and Their Management


Seizures in children vary widely in type, cause, and severity. Dr. Shinnar’s research helps clarify when to initiate antiepileptic drug therapy and when it might be safe to discontinue it. This is critical because unnecessary treatment can cause side effects, while delayed treatment can increase risks.


When to Start and Stop Medication


One of the key questions Dr. Shinnar investigates is the timing of antiepileptic drug therapy. For example:


  • After a child’s first seizure, should medication begin immediately or wait for a second seizure?

  • When can medication be safely stopped without risking seizure recurrence?


His studies provide evidence-based guidance that helps doctors balance treatment benefits and risks. This approach reduces unnecessary medication exposure while protecting children from further seizures.


Prognosis After a First Seizure


Dr. Shinnar’s long-term studies track children after their first seizure to understand their chances of developing epilepsy or experiencing seizure remission. These insights help families and clinicians set realistic expectations and plan care.


Prognosis After Stopping Medication


Another focus is the risk of seizure recurrence after stopping medication. Dr. Shinnar’s research identifies factors that predict which children are more likely to remain seizure-free and which may need ongoing treatment.


Research on Status Epilepticus and Prolonged Febrile Seizures


Status epilepticus is a serious condition where seizures last longer than 30 minutes without stopping. It requires urgent treatment to prevent brain damage or death. Dr. Shinnar is involved in the Established Status Epilepticus Treatment Trial (ESETT), which aims to find the best treatment when initial benzodiazepine therapy fails.


The ESETT Trial


This trial compares different therapies for convulsive status epilepticus in children and adults. Dr. Shinnar’s role on the executive committee helps ensure the study addresses critical clinical questions and improves treatment protocols.


Prolonged Febrile Seizures


Febrile seizures are the most common seizures in children, often triggered by fever. While usually benign, prolonged febrile seizures can have lasting effects. Dr. Shinnar’s current research investigates the long-term consequences of these seizures to better understand risks and guide follow-up care.


Focus on Childhood Absence Seizures


Childhood absence seizures, also known as petit-mal seizures, are the most common form of epilepsy in children. These brief seizures cause sudden lapses in awareness and can affect learning and behavior.


Dr. Shinnar studies the long-term outcomes of children with absence seizures, including:


  • How seizures evolve over time

  • Impact on cognitive development

  • Best treatment strategies to minimize side effects and improve quality of life


His work helps clinicians tailor care plans that address both seizure control and developmental needs.


Exploring Comorbidities and Family Impact


Epilepsy often comes with other challenges, such as learning difficulties, behavioral issues, and emotional stress. Dr. Shinnar’s research includes studying these comorbidities and how epilepsy affects families.


Understanding these broader effects is essential for providing holistic care. It helps healthcare providers offer support services, counseling, and resources that improve the overall well-being of children and their families.


Research in Autism and Neurological Conditions


In addition to epilepsy, Dr. Shinnar is involved in research on autism, a neurological condition increasingly diagnosed in childhood. His work explores overlaps between epilepsy and autism, aiming to improve diagnosis and treatment for children with both conditions.


Practical Takeaways for Families and Clinicians


Dr. Shinnar’s research offers several practical insights:


  • Not all seizures require immediate medication; careful evaluation guides treatment decisions.

  • Long-term studies provide clearer expectations about seizure outcomes and risks.

  • Status epilepticus needs rapid, effective treatment; ongoing trials aim to improve therapy.

  • Prolonged febrile seizures may have lasting effects, so follow-up is important.

  • Childhood absence seizures require attention to both seizure control and developmental support.

  • Epilepsy’s impact extends beyond seizures, affecting learning, behavior, and family dynamics.

  • Research on autism and epilepsy helps address complex neurological needs in children.


Families facing childhood seizures can benefit from consulting specialists who understand these nuances. Clinicians can use Dr. Shinnar’s findings to inform evidence-based care and improve patient outcomes.



Childhood seizures present many challenges, but advances in research and clinical care offer hope. Dr. Shlomo Shinnar’s work stands out for its depth and practical impact, guiding families and healthcare providers through complex decisions. By focusing on long-term outcomes, treatment timing, and the broader effects of epilepsy, his expertise helps children live healthier, fuller lives.


 
 
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